000			02411cam a22002657a 4500
001			17519564
005			20171003134634.0
008			121105s2011 si a b 001 0 eng d
010			_a 2012471988
020			_a9789814313704
020			_a981431370X
082	0	4	_a547.2 _223
245	0	0	_aOrganic synthesis via examination of selected natural products / _ceditor, David J. Hart.
260			_aSingapore ; _aHackensack, NJ : _bWorld Scientific, _cc2011.
300			_ax, 578 pages : _billustrations ; _c26 cm.
504			_aIncludes bibliographical references and index.
505	2		_aMachine generated contents note: Introduction -- Steroids -- Prostaglandins -- Pyrrolizidine Alkaloids -- Juvabione and the Vicinal Stereochemistry Problem -- Functional Group Reactivity Patterns and Difunctional Relationships -- Some Unnatural Products -- Twistane and Triquinacene -- Alkaloids -- Difunctional Relationships and the Importance of the Mannich Reaction -- Alkaloids from "Dart-Poison" Frogs -- Morphine and Oxidative Phenolic Coupling -- Olefin Synthesis and Cecropia Juvenile Hormone -- A Recent Example of Structure Determination Through Total Synthesis and Convergent Syntheses: Lasonolide A -- Ionophores: Calcimycin -- Erythromycin A Aglycone.
520	3		_aThis book is written for advanced graduate and undergraduate students to expose them to a variety of strategies for the synthesis of organic compounds. This is done largely within the context of natural products synthesis, but some unnatural products synthesis is also included. Multiple approaches to each group of synthesis targets are presented, and the approaches are compared with one another with an eye on similarities and differences. General problems in organic synthesis (for example, strategies for the preparation of 6-membered rings and 5-membered rings, the importance of oxidation state, the problem of acyclic diastereoselectivity, the problem of controlling absolute stereochemistry, the importance of functional group relationships) are introduced early in the book and revisited throughout the text within the context of a variety of structurally unrelated natural products.
650		0	_aOrganic compounds _xSynthesis. _92771
650		0	_aCompuestos inorgánicos _92772
650		0	_aNatural products _955
650		0	_aProductos naturales _91293
700	1		_aHart, David J. _92273 _eeditor
942			_2ddc _cLIBRO
999			_c243