Candida and candidiasis / edited by Richard A. Calderone, Georgetown University Medical Center, Washington, DC, Cornelius J. Clancy, Department of Medicine, Infectious Diseases Division, University of Pittsburgh, Pittsburgh, PA.

Contributor(s): Calderone, Richard A, 1942- [editor] | Clancy, Cornelius J [editor]Material type: TextTextLanguage: English Copyright date: Washington, DC : ASM Press, 2012Edition: Second editionDescription: xii, vii, 524 pages : illustrations (some color) ; 29 cmISBN: 9781555815394 Subject(s): Candidiasis | CandidaDDC classification: 616.9693 LOC classification: QR201.C27 | C365 2012NLM classification: QW 180.5.D38
Partial contents:
Candida: What Should Clinicians and Scientists Be Talking About? / Brad Spellberg, Kieren A. Marr, and Scott G. Filler -- The Organisms, Their Genomics, and Variability: An Introduction to the Medically Important Candida Species / Gary Moran, David Coleman, and Derek Sullivan -- Comparative Genomics of Candida Species / Geraldine Butler -- The Genetic Code of the Candida CTG Clade / Ana Catarina Gomes, Gabriela R. Moura, and Manuel A. S. Santos -- Genome Instability and DNA Repair / German Larriba and Richard A. Calderone -- Switching and Mating / David R. Soll -- Detection and Clinical Significance of Variability among Candida Isolates / Lois L. Hoyer -- Cell Cycle and Growth Control in Candida Species / Cheryl A. Gale and Judith Berman -- Host-Pathogen Interactions (The Host) -- Immunology of Invasive Candidiasis / Luigina Romani -- Mucosal Immunity to Candida albicans / Paul L. Fidel, Jr., and Mairi C. Noverr -- Innate Immunity to Candida Infections / Mihai G. Netea and Neil A. R. Gow -- Vaccines and Passive Immunity against Candidiasis rad Spellberg / Yue Fu, and Ashraf S. Ibrahim -- Salivary Histatins: Structure, Function, and Mechanisms of Antifungal Activity / Woon Sik Jang and Mira Edgerton -- Host-Pathogen Interactions (The Pathogen) -- The Cell Wall: Glycoproteins, Remodeling, and Regulation / Carol Munro and Mathias L. Richard -- Stress Responses in Candida / Alistair J. P. Brown, Ken Haynes, Neil A. R. Gow, and Janet Quinn -- Adhesins in Opportunistic Fungal Pathogens / Rebecca Zordan and Brendan Cormack -- Encounters with Mammalian Cells: Survival Strategies of Candida Species / Slavena Vylkova and Michael C. Lorenz -- Gene Expression during the Distinct Stages of Candidiasis / Duncan Wilson, Francois Mayer, and Bernhard Hube -- Biofilm Formation in Candida albicans / Jonathan Sewell Finkel and Aaron P. Mitchell -- Candida spp. in Microbial Populations and Communities: Molecular Interactions and Biological Importance / Amy E. Piispanen and Deborah A. Hogan -- Back to the Future: Candida Mitochondria and Energetics / Deepu Alex, Richard Calderone, and Dongmei Lee -- SECTION IV: Antifungal Drugs, Drug Resistance, and Discovery -- Antifungals: Drug Class, Mechanisms of Action, Pharmacokinetics/Pharmacodynamics, Drug-Drug Interactions, Toxicity, and Clinical Use / Jeniel E. Nett and David R. Andes -- The Impact of Antifungal Drug Resistance in the Clinic Russell / E. Lewis and Dimitrios P. Kontoyiannis -- Insights in Antifungal Drug Discovery / Francoise Gay-Andrieu, Jared May, Dongmei Li, Nuo Sun, Hui Chen, Richard Calderone, and Deepu Alex -- Multidrug Resistance Transcriptional Regulatory Networks in Candida / P. David Rogers and Katherine S. Barker -- SECTION V: Candidiasis, Evolving Diagnostics, and Treatment Paradigms -- Mucosal Candidiasis / Sanjay Revankar and Jack D. Sobel -- Systemic Candidiasis: Candidemia and Deep-Organ Infections Cornelius / J. Clancy and M. Hong Nguyen -- New Developments in Diagnostics and Management of Invasive Candidiasis Sujatha Krishnan and Luis Ostrosky-Zeichner -- The Epidemiology of Invasive Candidiasis / Michael A. Pfaller and Daniel J. Diekema -- SECTION VI: Cool Tools for Research: Cool Tools 1: Development and Application of a Candida albicans Two-Hybrid System / Bram Stynen, Patrick Van Dijck, and Helene Tournu -- Cool Tools 2: Development of a Candida albicans Cell Surface Protein Microarray / A. Brian Mochon -- Cool Tools 3: Large-Scale Genetic Interaction Screening in Candida albicans / Yeissa Chabrier-Rosello, Anuj Kumar, and Damian Krysan -- Cool Tools 4: Imaging Candida Infections in the Live Host / Soumya Mitra, Thomas H. Foster, and Melanie Wellington -- Cool Tools 5: The Candida albicans ORFeome Project / Melanie Legrand, Carol Munro, and Christophe d'Enfert.
Abstract: The underlying mechanisms of Candida and candidiasis and promising new directions in drug discovery and treatment. * Reviews all aspects of this common fungal pathogen and its impact on human health, from the basic biology of Candida albicans to the clinical management of candidiasis.
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Includes index.

Includes bibliographical references.

Candida: What Should Clinicians and Scientists Be Talking About? / Brad Spellberg, Kieren A. Marr, and Scott G. Filler -- The Organisms, Their Genomics, and Variability: An Introduction to the Medically Important Candida Species / Gary Moran, David Coleman, and Derek Sullivan -- Comparative Genomics of Candida Species / Geraldine Butler -- The Genetic Code of the Candida CTG Clade / Ana Catarina Gomes, Gabriela R. Moura, and Manuel A. S. Santos -- Genome Instability and DNA Repair / German Larriba and Richard A. Calderone -- Switching and Mating / David R. Soll -- Detection and Clinical Significance of Variability among Candida Isolates / Lois L. Hoyer -- Cell Cycle and Growth Control in Candida Species / Cheryl A. Gale and Judith Berman -- Host-Pathogen Interactions (The Host) -- Immunology of Invasive Candidiasis / Luigina Romani -- Mucosal Immunity to Candida albicans / Paul L. Fidel, Jr., and Mairi C. Noverr -- Innate Immunity to Candida Infections / Mihai G. Netea and Neil A. R. Gow -- Vaccines and Passive Immunity against Candidiasis rad Spellberg / Yue Fu, and Ashraf S. Ibrahim -- Salivary Histatins: Structure, Function, and Mechanisms of Antifungal Activity / Woon Sik Jang and Mira Edgerton -- Host-Pathogen Interactions (The Pathogen) -- The Cell Wall: Glycoproteins, Remodeling, and Regulation / Carol Munro and Mathias L. Richard -- Stress Responses in Candida / Alistair J. P. Brown, Ken Haynes, Neil A. R. Gow, and Janet Quinn -- Adhesins in Opportunistic Fungal Pathogens / Rebecca Zordan and Brendan Cormack -- Encounters with Mammalian Cells: Survival Strategies of Candida Species / Slavena Vylkova and Michael C. Lorenz -- Gene Expression during the Distinct Stages of Candidiasis / Duncan Wilson, Francois Mayer, and Bernhard Hube -- Biofilm Formation in Candida albicans / Jonathan Sewell Finkel and Aaron P. Mitchell -- Candida spp. in Microbial Populations and Communities: Molecular Interactions and Biological Importance / Amy E. Piispanen and Deborah A. Hogan -- Back to the Future: Candida Mitochondria and Energetics / Deepu Alex, Richard Calderone, and Dongmei Lee -- SECTION IV: Antifungal Drugs, Drug Resistance, and Discovery -- Antifungals: Drug Class, Mechanisms of Action, Pharmacokinetics/Pharmacodynamics, Drug-Drug Interactions, Toxicity, and Clinical Use / Jeniel E. Nett and David R. Andes -- The Impact of Antifungal Drug Resistance in the Clinic Russell / E. Lewis and Dimitrios P. Kontoyiannis -- Insights in Antifungal Drug Discovery / Francoise Gay-Andrieu, Jared May, Dongmei Li, Nuo Sun, Hui Chen, Richard Calderone, and Deepu Alex -- Multidrug Resistance Transcriptional Regulatory Networks in Candida / P. David Rogers and Katherine S. Barker -- SECTION V: Candidiasis, Evolving Diagnostics, and Treatment Paradigms -- Mucosal Candidiasis / Sanjay Revankar and Jack D. Sobel -- Systemic Candidiasis: Candidemia and Deep-Organ Infections Cornelius / J. Clancy and M. Hong Nguyen -- New Developments in Diagnostics and Management of Invasive Candidiasis Sujatha Krishnan and Luis Ostrosky-Zeichner -- The Epidemiology of Invasive Candidiasis / Michael A. Pfaller and Daniel J. Diekema -- SECTION VI: Cool Tools for Research: Cool Tools 1: Development and Application of a Candida albicans Two-Hybrid System / Bram Stynen, Patrick Van Dijck, and Helene Tournu -- Cool Tools 2: Development of a Candida albicans Cell Surface Protein Microarray / A. Brian Mochon -- Cool Tools 3: Large-Scale Genetic Interaction Screening in Candida albicans / Yeissa Chabrier-Rosello, Anuj Kumar, and Damian Krysan -- Cool Tools 4: Imaging Candida Infections in the Live Host / Soumya Mitra, Thomas H. Foster, and Melanie Wellington -- Cool Tools 5: The Candida albicans ORFeome Project / Melanie Legrand, Carol Munro, and Christophe d'Enfert.

The underlying mechanisms of Candida and candidiasis and promising new directions in drug discovery and treatment. * Reviews all aspects of this common fungal pathogen and its impact on human health, from the basic biology of Candida albicans to the clinical management of candidiasis.

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