Targeted delivery of small and macromolecular drugs / edited by Ajit S. Narang and Ram I. Mahato.

Contributor(s): Mahato, Ram I [editor] | Narang, Ajit S [editor]Material type: TextTextLanguage: English Copyright date: Boca Raton, FL : CRC Press/Taylor & Francis, 2010Edition: First EditionDescription: xvi, 614 pages : illustrations ; 26 cmISBN: 9781420087727; 142008772X (alk. paper)Subject(s): Drug targeting | Drug Delivery Systems | Drug Administration Routes | Segmentación de drogas | Sistemas de administración de fármacos | Rutas de administración de medicamentosDDC classification: 615.7 LOC classification: RM301.63 | .T365 2010NLM classification: 2010 G-405 | QV 785
Partial contents:
Chapter 1 Therapeutic potential of targeted drug delivery / Ajit S. Narang and Ram I. Mahato -- Part I Active targeting -- Chapter 2 Antibody therapies for liver malignancy and transplantation / John M. Luk and Kwong-Fai Wong -- Chapter 3 Transferrin receptor-mediated transcytosis in intestinal epithelial cells for gastrointestinal absorption of protein drugs / Nurmamet Amet ... [et al.] -- Chapter 4 Ionizing radiation for tumor targeted drug delivery / Roberto Diaz, Li Zhou, and Dennis E. Hallahan -- Part II Nucleic acid delivery and targeting -- Chapter 5 Recent advances in gene expression and delivery systems / Ravikiran Panakanti and Ram I. Mahato -- Chapter 6 Cellular barriers for nucleic acid delivery and targeting / Arto Urtti -- Chapter 7 Targeted delivery systems of non-viral nucleic acid-based therapeutics / Ga Yong Shim ... [et al.] -- Chapter 8 Delivery and targeting of oligonucleotides and siRNA / Ningning Yang and Ram I. Mahato -- Chapter 9 Liposomes for non-viral gene delivery / Jiasheng Tu ... [et al.] -- Part III Intracellular/organelle-Specific strategies -- Chapter 10 Delivering the bullet to the right intracellular target : a cellular perspective on drug delivery / Maria Teresa Tarragâo-Trani and Brian Storrie -- Chapter 11 Mitochondria-targeted drug delivery / Volkmar Weissig and Gerard G. M. D'Souza -- Part IV Produg strategies -- Chapter 12 Site-specific prodrug activation strategies for targeted drug action / Mark D. Erion -- Chapter 13 Enzyme-activated prodrug strategies for targeted drug action / Jarkko Rautio ... [et al.] -- Part V Organ-or tissue specific drug delivery -- Chapter 14 Targeting colon and kidney : pathophysiological determinants of design strategy / Ajit S. Narang and Ram I. Mahato -- Chapter 15 Principles and practice of pulmonary drug delivery / Vivek Gupta, Chandan Thomas, and Fakhrul Ahsan -- Chapter 16 Recent advances in ocular drug delivery : role of transporters, receptors, and nanocarriers / Gyan P. Mishra ... [et al.] -- Part VI Polimer-drug conjugates and micelles -- Chapter 17 Injectable polymers for regional drug delivery / Rajendra P. Pawar ... [et al.] -- Chapter 18 Polymer-drug conjugates / Lucienne Juillerat-Jeanneret and Feride Cengelli -- Chapter 19 Polymer micelles for drug delivery / Sungwon Kim and Kinam Park -- Part VII Stimumi-responsive systems -- Chapter 20 Multifunctional stimuli-responsive nanoparticles for targeted delivery of small and macromolecular therapeutics / Srinivas Ganta, Arun Iyer, and Mansoor Amiji -- Chapter 21 Physiological stress responsive gene regulation systems for tissue targeting / Hyun Ah Kim and Minhyung Lee.
Abstract: Site-specific drug delivery and targeting has attracted much research interest, but because of the wide array of challenges faced in the development of these systems, only a few targeted therapies have made it to clinics. This volume includes a review of various aspects of these drug delivery approaches.
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Item type Current library Call number Copy number Status Date due Barcode Item holds
Libro académico Libro académico Biblioteca del Campus
615.7 T185 2010 (Browse shelf (Opens below)) Ej. 1 Available 001491
Total holds: 0

Includes index.

Includes bibliographical references.

Chapter 1 Therapeutic potential of targeted drug delivery / Ajit S. Narang and Ram I. Mahato -- Part I Active targeting -- Chapter 2 Antibody therapies for liver malignancy and transplantation / John M. Luk and Kwong-Fai Wong -- Chapter 3 Transferrin receptor-mediated transcytosis in intestinal epithelial cells for gastrointestinal absorption of protein drugs / Nurmamet Amet ... [et al.] -- Chapter 4 Ionizing radiation for tumor targeted drug delivery / Roberto Diaz, Li Zhou, and Dennis E. Hallahan -- Part II Nucleic acid delivery and targeting -- Chapter 5 Recent advances in gene expression and delivery systems / Ravikiran Panakanti and Ram I. Mahato -- Chapter 6 Cellular barriers for nucleic acid delivery and targeting / Arto Urtti -- Chapter 7 Targeted delivery systems of non-viral nucleic acid-based therapeutics / Ga Yong Shim ... [et al.] -- Chapter 8 Delivery and targeting of oligonucleotides and siRNA / Ningning Yang and Ram I. Mahato -- Chapter 9 Liposomes for non-viral gene delivery / Jiasheng Tu ... [et al.] -- Part III Intracellular/organelle-Specific strategies -- Chapter 10 Delivering the bullet to the right intracellular target : a cellular perspective on drug delivery / Maria Teresa Tarragâo-Trani and Brian Storrie -- Chapter 11 Mitochondria-targeted drug delivery / Volkmar Weissig and Gerard G. M. D'Souza -- Part IV Produg strategies -- Chapter 12 Site-specific prodrug activation strategies for targeted drug action / Mark D. Erion -- Chapter 13 Enzyme-activated prodrug strategies for targeted drug action / Jarkko Rautio ... [et al.] -- Part V Organ-or tissue specific drug delivery -- Chapter 14 Targeting colon and kidney : pathophysiological determinants of design strategy / Ajit S. Narang and Ram I. Mahato -- Chapter 15 Principles and practice of pulmonary drug delivery / Vivek Gupta, Chandan Thomas, and Fakhrul Ahsan -- Chapter 16 Recent advances in ocular drug delivery : role of transporters, receptors, and nanocarriers / Gyan P. Mishra ... [et al.] -- Part VI Polimer-drug conjugates and micelles -- Chapter 17 Injectable polymers for regional drug delivery / Rajendra P. Pawar ... [et al.] -- Chapter 18 Polymer-drug conjugates / Lucienne Juillerat-Jeanneret and Feride Cengelli -- Chapter 19 Polymer micelles for drug delivery / Sungwon Kim and Kinam Park -- Part VII Stimumi-responsive systems -- Chapter 20 Multifunctional stimuli-responsive nanoparticles for targeted delivery of small and macromolecular therapeutics / Srinivas Ganta, Arun Iyer, and Mansoor Amiji -- Chapter 21 Physiological stress responsive gene regulation systems for tissue targeting / Hyun Ah Kim and Minhyung Lee.

Site-specific drug delivery and targeting has attracted much research interest, but because of the wide array of challenges faced in the development of these systems, only a few targeted therapies have made it to clinics. This volume includes a review of various aspects of these drug delivery approaches.

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