000 03704cam a2200373 a 4500
001 16040786
005 20150513155852.0
008 100105s2010 enka b 001 0 eng
010 _a 2010000127
015 _aGBB046108
_2bnb
016 7 _a015522281
_2Uk
020 _a9780521882736
020 _a0521882737 (hardback)
035 _a(OCoLC)ocn500241736
040 _aDLC
_cDLC
_dYDXCP
_dBWKUK
_dBWK
_dCDX
_dUKM
_dBWX
_dDLC
050 0 0 _aQH604
_b.M63 2010
082 0 0 _a571.6
_222
245 0 0 _aNetworks in cell biology /
_cedited by M. Buchanan ... [et al.].
260 _aCambridge ;
_aNew York :
_bCambridge University Press,
_c2010.
300 _ax, 271 p. :
_bill. ;
_c26 cm.
504 _aIncludes bibliographical references and index.
505 8 _aMachine generated contents note: Introduction; 1. Network views of the cell Paolo De Los Rios and Michele Vendruscolo; 2. Transcriptional regulatory networks Sarath Chandra Janga and M. Madan Babu; 3. Transcription factors and gene regulatory networks Matteo Brilli, Elissa Calistri and Pietro Lió; 4. Experimental methods for protein interaction identification Peter Uetz, Björn Titz, Seesandra V. Rajagopala and Gerard Cagney; 5. Modeling protein interaction networks Francesco Rao; 6. Dynamics and evolution of metabolic networks Daniel Segre;; 7. Hierarchical modularity in biological networks: the case of metabolic networks Erzse;bet Ravasz Regan; 8. Signalling networks Gian Paolo Rossini; Appendix 1. Complex networks: from local to global properties D. Garlaschelli and G. Caldarelli; Appendix 2. Modelling the local structure of networks D. Garlaschelli and G. Caldarelli; Appendix 3. Higher-order topological properties S. Ahnert, T. Fink and G. Caldarelli; Appendix 4. Elementary mathematical concepts A. Gabrielli and G. Caldarelli; References.
520 _a"The science of complex biological networks is transforming research in areas ranging from evolutionary biology to medicine. This is the first book on the subject, providing a comprehensive introduction to complex network science and its biological applications. With contributions from key leaders in both network theory and modern cell biology, this book discusses the network science that is increasingly foundational for systems biology and the quantitative understanding of living systems. It surveys studies in the quantitative structure and dynamics of genetic regulatory networks, molecular networks underlying cellular metabolism, and other fundamental biological processes. The book balances empirical studies and theory to give a unified overview of this interdisciplinary science. It is a key introductory text for graduate students and researchers in physics, biology and biochemistry, and presents ideas and techniques from fields outside the reader's own area of specialization"--Provided by publisher.
520 _a"Biologists now have access to a virtually complete map of all the genes in the human genome, and in the genomes of many other species. They are aggressively assembling a similarly detailed knowledge of the proteome, the full collection of proteins encoded by those genes, and the transcriptome, the diverse set of mRNA"--Provided by publisher.
650 0 _aCellular control mechanisms.
650 0 _aBiological systems.
650 0 _aGene regulatory networks.
650 0 _aSystem analysis.
700 1 _aBuchanan, M.
_q(Mark),
_d1961-
856 4 2 _3Cover image
_uhttp://assets.cambridge.org/97805218/82736/cover/9780521882736.jpg
906 _a7
_bcbc
_corignew
_d1
_eecip
_f20
_gy-gencatlg
942 _2ddc
_cLIBRO
955 _bxj12 2010-01-05
_cxj12 2010-01-05 ONIX (telework) to STM
_axe1- 2010-08-16 2 copies rec'd., to CIP ver.
999 _c838