Organic synthesis via examination of selected natural products / editor, David J. Hart.

Includes bibliographical references and index.

Machine generated contents note: Introduction -- Steroids -- Prostaglandins -- Pyrrolizidine Alkaloids -- Juvabione and the Vicinal Stereochemistry Problem -- Functional Group Reactivity Patterns and Difunctional Relationships -- Some Unnatural Products -- Twistane and Triquinacene -- Alkaloids -- Difunctional Relationships and the Importance of the Mannich Reaction -- Alkaloids from "Dart-Poison" Frogs -- Morphine and Oxidative Phenolic Coupling -- Olefin Synthesis and Cecropia Juvenile Hormone -- A Recent Example of Structure Determination Through Total Synthesis and Convergent Syntheses: Lasonolide A -- Ionophores: Calcimycin -- Erythromycin A Aglycone.

This book is written for advanced graduate and undergraduate students to expose them to a variety of strategies for the synthesis of organic compounds. This is done largely within the context of natural products synthesis, but some unnatural products synthesis is also included. Multiple approaches to each group of synthesis targets are presented, and the approaches are compared with one another with an eye on similarities and differences. General problems in organic synthesis (for example, strategies for the preparation of 6-membered rings and 5-membered rings, the importance of oxidation state, the problem of acyclic diastereoselectivity, the problem of controlling absolute stereochemistry, the importance of functional group relationships) are introduced early in the book and revisited throughout the text within the context of a variety of structurally unrelated natural products.