Co-existence and co-release of classical neurotransmitters : ex uno plures / Rafael Gutiérrez, editor. - First Edition - ix, 275 pages, [16] pages of plates : illustrations (some colours) ; 25 cm.

Includes bibliographical references and index.

Coexistence of neuromessenger molecules: a perspective -- Ex uno plures: out of one, many -- Mechanisms of synapse formation: activity-dependent selection of neurotransmitters and receptors -- Co-release of norepinephrine and acetylcholine by mammalian sympathetic neurons: regulation by target-derived signaling -- GABA, glycine, and glutamate co-release at developing inhibitory synapses -- GABA is the main neurotransmitter released from mossy fiber terminals in the developing rat hippocampus -- Postsynaptic determinants of inhibitory transmission at mixed GABAergic/glycinergic synapses -- Glutamate co-release by monoamine neurons -- Dopamine and serotonin crosstalk within the dopaminergic and serotonergic systems -- The dual glutamatergic/GABAergic phenotype of hippocampal granule cells -- Synaptic co-release of ATP and GABA -- The co-release of glutamate and acetylcholine in the vertebrate nervous system -- Colocalization and cotransmission of classical neurotransmitters: an invertebrate perspective -- E pluribus unum: out of many, one.

Until recently, many neuroscientists were skeptical of the idea that classical neurotransmitters could be co-released from neurons. It isnow common knowledge, though, that the "one neuron, one neurotransmitter" postulate is the exception rather than the rule. Co-Existence and Co-Release of Classical Neurotransmitters provides readers with a comprehensive overview of research from the worldâ€s leading neuroscience authors, all of whom have discovered and studied the co-existence or co-release of several pairs of neurotransmitters in neural networks. Their reviews include novel aspects of transmitter combinations, such as NA-ACh, monoamines-glutamate, ACh-glutamate, cross-talk between monoamines, GABA and ATP, and various combinations of aminoacid transmitters. Co-Existence and Co-Release of Classical Neurotransmitters will be particularly useful to neuroscience graduate students, academics, and researchers in synaptic physiology and synaptic plasticity. This book is the first of its kind to center on the timely issue of co-release of neurotransmitters, and serves as an important contribution to the re-consideration of this idea in other brain regions. About the Editor: Dr. Rafael Gutiérrezwas among the first to study the physiological impact of the co-existence of glutamate and GABA in the hippocampus, particularly the developmental and activity-dependent expression of GABAergic markers in granule cells. Since 1997, Dr. Gutiérrez has been a professor of neurosciences at the Center for Research and Advanced Studies (CINVESTAV) in Mexico City. He recieved his PhD in Neurosciences from the National University of Mexico in 1993 and, under the prestigious Alexander von Humboldt Research Scholarship, worked for three years withpathophysiology expertUwe Heinemann in Germany.

9780387096216 0387096213 (alk. paper)


GBA890681 bnb

101493840 DNLM 014673968 Uk

Neural transmission
Neurotransmitter Agents
Transmisión neuronal
Agentes neurotransmisores

QP364.7 / .C62 2009

573.854 / C6521 2009

2009 A-683 QV 126 / C652 2009