Epigenetics /
Epigenetics /
editors, C. David Allis, The Rockefeller University, New York, Marie-Laure Caparros, London, Thomas Jenuwein, Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Danny Reinberg, Howard Hughes Medical Institute, New York University School of Medicine-Smilow Research Center ; associate editor, Monika Lachner, Max Planck Institute of Immunobiology and Epigenetics, Freiburg.
- Second edition.
- xiv, 984 pages : illustrations (chiefly color) ; 29 cm
Includes bibliographical references and index.
A Brief History of Epigenetics -- The Next Generation: Young Scientists Forging Exciting New Discoveries in Epigenetic Research -- Overview and Concepts -- Writers and Readers of Histone Acetylation: Structure, Mechanism, and Inhibition -- Erasers of Histone Acetylation: The Histone Deacetylase Enzymes -- Structural and Functional Coordination of DNA and Histone Methylation -- A Structural Perspective on Readout of Epigenetic Histone and DNA Methylation Marks -- Epigenetics in Saccharomyces cerevisiae -- Epigenetic Regulation of Chromatin States in Schizosaccharomyces pombe -- Neurospora crassa, a Model System for Epigenetics Research -- Epigenetics of Ciliates -- Position-Effect Variegation, Heterochromatin Formation, and Gene Silencing in Drosophila -- Epigenetic Regulation in Plants -- The Use of Mouse Models to Study Epigenetics -- DNA Methylation in Mammals -- RNAi and Heterochromatin Assembly -- Transcriptional Silencing by Polycomb-Group Proteins -- Transcriptional Regulation by Trithorax-Group Proteins -- Long-Range Chromatin Interactions -- Histone Variants and Epigenetics -- Nucleosome Remodeling and Epigenetics -- Maintenance of Epigenetic Information -- Regulation of the X Chromosomes in Caenorhabditis elegans -- Dosage Compensation in Drosophila -- Dosage Compensation in Mammals -- Genomic Imprinting in Mammals -- Germline and Pluripotent Stem Cells -- Induced Pluripotency and Epigenetic Reprogramming -- Epigenetic Control of Immunity -- Metabolic Signaling to Chromatin -- Epigenetic Regulation in Plant Responses to the Environment -- Histone and DNA Modifications as Regulators of Neuronal Development and Function -- Epigenetics and Human Disease -- Epigenetic Determinants of Cancer -- Histone Modifications and Cancer -- The Necessity of Chromatin: AView in Perspective.
In many biological processes the regulation of gene expression involves epigenetic mechanisms. In this new edition of Epigenetics, 36 chapters written by experts in the field introduce and explain epigenetic effects from many perspectives. These include the varied molecular mechanisms underpinning epigenetic regulation, discussion of cellular processes that rely on this kind of regulation, and surveys of model organisms in which epigenetic effects have been most studied.
9781936113590
2014029474
Genetic regulation
Regulación genética
Epigenesis, Genetic.
Gene Expression Regulation
Regulación de expresión génica
QH450 / .E655 2015
572.865
QU 475
Includes bibliographical references and index.
A Brief History of Epigenetics -- The Next Generation: Young Scientists Forging Exciting New Discoveries in Epigenetic Research -- Overview and Concepts -- Writers and Readers of Histone Acetylation: Structure, Mechanism, and Inhibition -- Erasers of Histone Acetylation: The Histone Deacetylase Enzymes -- Structural and Functional Coordination of DNA and Histone Methylation -- A Structural Perspective on Readout of Epigenetic Histone and DNA Methylation Marks -- Epigenetics in Saccharomyces cerevisiae -- Epigenetic Regulation of Chromatin States in Schizosaccharomyces pombe -- Neurospora crassa, a Model System for Epigenetics Research -- Epigenetics of Ciliates -- Position-Effect Variegation, Heterochromatin Formation, and Gene Silencing in Drosophila -- Epigenetic Regulation in Plants -- The Use of Mouse Models to Study Epigenetics -- DNA Methylation in Mammals -- RNAi and Heterochromatin Assembly -- Transcriptional Silencing by Polycomb-Group Proteins -- Transcriptional Regulation by Trithorax-Group Proteins -- Long-Range Chromatin Interactions -- Histone Variants and Epigenetics -- Nucleosome Remodeling and Epigenetics -- Maintenance of Epigenetic Information -- Regulation of the X Chromosomes in Caenorhabditis elegans -- Dosage Compensation in Drosophila -- Dosage Compensation in Mammals -- Genomic Imprinting in Mammals -- Germline and Pluripotent Stem Cells -- Induced Pluripotency and Epigenetic Reprogramming -- Epigenetic Control of Immunity -- Metabolic Signaling to Chromatin -- Epigenetic Regulation in Plant Responses to the Environment -- Histone and DNA Modifications as Regulators of Neuronal Development and Function -- Epigenetics and Human Disease -- Epigenetic Determinants of Cancer -- Histone Modifications and Cancer -- The Necessity of Chromatin: AView in Perspective.
In many biological processes the regulation of gene expression involves epigenetic mechanisms. In this new edition of Epigenetics, 36 chapters written by experts in the field introduce and explain epigenetic effects from many perspectives. These include the varied molecular mechanisms underpinning epigenetic regulation, discussion of cellular processes that rely on this kind of regulation, and surveys of model organisms in which epigenetic effects have been most studied.
9781936113590
2014029474
Genetic regulation
Regulación genética
Epigenesis, Genetic.
Gene Expression Regulation
Regulación de expresión génica
QH450 / .E655 2015
572.865
QU 475