Immunity against mucosal pathogens / Michael Vajdy, editor. - First Edition - xvi, 524 pages : illustrations (some colours) ; 25 cm.

Includes index.

Includes bibliographical references.

Part I: Structure and Cells of Mucosal Tissues -- 1 The Intestinal Epithelium: The Interface Between Host and Pathogen -- 2 Structure of the Respiratory and Female Genitourinary Tracts -- Part II: Immunology of Mucosal Tissues -- 3 The Mucosal B-Cell System -- 4 Bridging Mucosal Innate Immunity to the Adaptive Immune System -- 5 Intestinal Bacteria: Mucosal Tissue Development and Gut Homeostasis -- Part III: Gastrointestinal Pathogens -- 6 Mucosal Immune Responses Against Enterotoxigenic Escherichia coli [ETEC] in Humans -- 7 Cholera Immunity and Cholera Vaccination -- 8 Helicobacter pylori Pathogenesis and Vaccines -- 9 Immunology of Norovirus Infection -- 10 Intestinal and Systemic Immunity to Rotavirus in Animal Models and Humans -- Part IV: Respiratory Pathogens -- 11 Mucosal Control of Streptococcus pneumoniae Infections -- 12 Neisseria meningitidis -- 13 Mucosal Immunity Against Anthrax -- 14 Structure, Immunopathogenesis and Vaccines Against SARS Coronavirus -- 15 Influenza Virus Pathogenesis and Vaccines --
Part V: Genital Pathogens -- 16 Immunity Against Chlamydia trachomatis -- 17 HIV and the Mucosa: No Safe Haven -- 18 Mucosal Vaccination Against HIV-1 -- Part VI: Mucosal Vaccine Approaches -- 19 Formulations and Delivery Systems for Mucosal Vaccines.

Surprisingly what separates us from the open environment all around us sometimes is a single layer of epithelial cells. It is at these seemingly fragile sites that most pathogens, including HIV, influenza, emerging and biodefense agents, gain access to our inside milieu. While there are major similarities between the cells and the immune responses generated at the mucosal membranes of the gastrointestinal and respiratory tracts together with the genitourinary tract, there are also important differences.

9781402084119 9781402084126

Pathogenic bacteria
Emerging infectious diseases
Bacteria patogénica
Enfermedades infecciosas emergentes

616.079 / I336 2008