Drug disposition and pharmacokinetics :
Curry, Stephen H.
Drug disposition and pharmacokinetics : from principles to applications / Stephen H. Curry, Robin Whelpton. - Chichester, West Sussex : Wiley-Blackwell, 2011. - xix, 365 p. : ill. ; 26 cm.
Includes bibliographical references and index.
Chemical introduction : sources, classification, and chemical properties of drugs -- Drug administration and distribution -- Drug elimination -- Elementary pharmacokinetics -- More complex and model independent pharmacokinetic models -- Kinetics of metabolism and excretion -- Further consideration of clearance, and physiological modelling -- Drug formulation : bioavailability, bioequivalence and controlled-release preparations -- Factors affecting plasma concentrations -- Pharmacogenetics and pharmacogenomics -- Developmental pharmacology and age-related phenomena -- Effects of disease on drug disposition -- Quantitative pharmacological relationships -- Simultaneous measurement of concentrations and effect, and pharmacokinetic/pharmacodynamic (PK/PD) modelling -- Drug monitoring in therapeutics -- Drug interactions -- Drug metabolism and pharmacokinetics in toxicology.
9780470684467 0470684461 (cloth)
2010003126
GBB052569 bnb
101523934 DNLM 015535117 Uk
Pharmacokinetics.
Biopharmaceutics.
Drugs--Metabolism.
Pharmacokinetics.
Biopharmaceutics.
Pharmaceutical Preparations--metabolism.
RM301.5 / .C863 2011
615/.7
2011 A-481 QV 38 / C976da 2011
Drug disposition and pharmacokinetics : from principles to applications / Stephen H. Curry, Robin Whelpton. - Chichester, West Sussex : Wiley-Blackwell, 2011. - xix, 365 p. : ill. ; 26 cm.
Includes bibliographical references and index.
Chemical introduction : sources, classification, and chemical properties of drugs -- Drug administration and distribution -- Drug elimination -- Elementary pharmacokinetics -- More complex and model independent pharmacokinetic models -- Kinetics of metabolism and excretion -- Further consideration of clearance, and physiological modelling -- Drug formulation : bioavailability, bioequivalence and controlled-release preparations -- Factors affecting plasma concentrations -- Pharmacogenetics and pharmacogenomics -- Developmental pharmacology and age-related phenomena -- Effects of disease on drug disposition -- Quantitative pharmacological relationships -- Simultaneous measurement of concentrations and effect, and pharmacokinetic/pharmacodynamic (PK/PD) modelling -- Drug monitoring in therapeutics -- Drug interactions -- Drug metabolism and pharmacokinetics in toxicology.
9780470684467 0470684461 (cloth)
2010003126
GBB052569 bnb
101523934 DNLM 015535117 Uk
Pharmacokinetics.
Biopharmaceutics.
Drugs--Metabolism.
Pharmacokinetics.
Biopharmaceutics.
Pharmaceutical Preparations--metabolism.
RM301.5 / .C863 2011
615/.7
2011 A-481 QV 38 / C976da 2011